On February 28, 2024, Professor Chen Liang’s team from the Neurosurgery Department at Huashan Hospital, Fudan University, successfully performed a "cell-level" resection of an epileptic focus. Assisted by the EndoSCell? handheld intraoperative microscope, they achieved precision removal at the cellular level.
Surgical effectiveness is closely linked to the complete removal of the epileptogenic focus. Typically, doctors use neuroimaging (such as MRI or CT), electroencephalograms (EEG), and neuropsychological tests to determine the location and type of seizures.
The main difference from traditional surgery lies in the use of EndoSCell?, the world's only handheld intraoperative microscope that provides real-time visualization of cellular structures during surgery, developed by Dendrite Precision, a leader in global optics. In this procedure, the epileptogenic focus in the right frontal lobe was removed under intraoperative navigation and electrophysiological monitoring. Following the main resection, EndoSCell? performed a nearly 10-minute sliding scan across three critical areas along the margins. A residual lesion was identified and resected, followed by craniotomy closure and other steps.
▲陳亮教授在癲癇病灶切除術(shù)中使用EndoScell輔助檢查切緣
Dr. Zou Xiang from the Neurosurgery Department at Huashan Hospital, Fudan University, summarized: "This epilepsy surgery was supported by multiple advanced technologies. Intraoperatively, we used electrophysiological monitoring and the EndoSCell? to assess the epileptogenic focus. The EndoSCell? confirmed the surgical margins as normal, showing typical neuronal and brain white matter structures." The medical team will continue long-term follow-up to monitor the patient's recovery.
The success of this surgery marks a major breakthrough in achieving cell-level precision in epileptogenic focus resection in China. According to the Chinese Anti-Epilepsy Association, there are at least 9 million epilepsy patients in China, about 30% of whom require surgical treatment. With the widespread adoption of cell-level precision surgery, millions of patients stand to benefit in the future.
